The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell. You can find TWiV #412 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV412.mp3″] Click arrow to play Download TWiV 412 (73 MB .mp3, 121 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
Oncogenes of DNA tumor viruses encode proteins that cause cells to divide incessantly, eventually leading to formation of a tumor. These oncoproteins have now been found to antagonize the innate immune response of the cell (link to paper). Most cells encountered by viruses are not dividing, and hence do not efficiently support viral DNA synthesis. The …
The TWiV team is together in New York City for a conversation with Nobel Laureate Harold Varmus about his remarkable career in science. You can find TWiV #400 at microbe.tv/twiv, or listen/watch below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV400.mp3″] Click arrow to play Download TWiV 400 (101 MB .mp3, 139 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!
A major new feature of the fourth edition of Principles of Virology is the inclusion of 26 video interviews with leading scientists who have made significant contributions to the field of virology. For the chapter on Transformation and Oncogenesis, Vincent spoke with Nobel Laureate J. Michael Biship, of the University of California, San Francisco, about his career and his work on oncogenes.
On episode #374 of the science show This Week in Virology, the TWiVniks consider the role of a cell enzyme that removes a protein linked to the 5′-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt’s lymphoma. You can find TWiV #374 at microbe.tv/twiv.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove Vincent, Dickson, Rich, and Alan answer listener questions about XMRV, cytomegalovirus, latency, shingles vaccine, myxomavirus and rabbits, and more. Please help us by taking our listener survey. Click the arrow above to play, or right-click to download TWiV 165 (61 MB .mp3, 102 minutes). Subscribe to TWiV …