A Viral Risk Factor for Multiple Sclerosis
Several new lines of evidence suggest that Epstein-Barr virus infection may be a risk factor for the development of multiple sclerosis.
multiple sclerosis
TWiV 869: Epstein-Barr virus and MS, a perfect storm
TWiV reviews epidemiological and experimental evidence that infection with Epstein-Barr virus leads to the production of antibodies against a viral protein that cross-react with a human protein, leading to multiple sclerosis.
TWiV 176: Ave, magi virorum!
On episode #176 of the podcast This Week in Virology, Vincent, Alan, and Rich answer listener email about MS, CFS, EBV, B cells, virii, influenza B, scientific papers, and more. You can find TWiV #176 at www.microbe.tv/twiv.
TWiV #26: Poxviruses
On episode #26 of the podcast “This Week in Virology”, Vincent, Alan, and Rich Condit converse about induction of polyomavirus replication in multiple sclerosis patients treated with the MS drug Tysabri, the extent of human polyomavirus infection, selection of influenza vaccines for the 2009-10 season, cowpox virus transmission from animals to humans, vaccinia-like virus infecting …
Polyomavirus JC, multiple sclerosis, Tysabri, and an anti-malaria drug
Biogen has announced that an anti-malaria compound may be useful for treating a brain infection, progressive multifocal leukoencephalopathy (PML), that is an adverse effect of the company’s multiple sclerosis/Crohn’s disease drug Tysabri. How does JC virus fit into this story? Tysabri is the trade name for Natalizumab, a monoclonal antibody against the cellular protein alpha-4 integrin. …
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