Long Covid

Trial By Error: Study Finds “Elevated Brain Injury Markers and Reduced Grey Matter Volume” a Year After Hospitalization for COVID-19

By David Tuller, DrPH A British study of neurological sequelae in patients many months after hospitalization for COVID-19 has found that “post acute cognitive deficits…were associated with elevated brain injury markers in serum and reduced grey matter volume,” according to a pre-print posted earlier this week. (A pre-print is a paper that has not yet …

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Trial By Error: Interview with Founders of The Sick Times, a New Online Publication

By David Tuller, DrPH Earlier this month, Betsy Ladyzhets and Miles Griffis, two smart, young American journalists, announced the launch The Sick Times, an online publication focused on long Covid and related post-acute infection syndromes, including ME/CFS. I have met both of them in the last couple of years and have been impressed with their …

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Trial By Error: David Putrino on New Nature Study of Long Covid Immune Profiling

By David Tuller, DrPH I’ve posted two past interviews with David Putrino (here and here) about long Covid, ME/CFS, and related issues. Dr Putrino, a neuroscientist and physical therapist, is director of rehabilitation innovation at the Mt Sinai Health System in New York. Early in the pandemic, the rehabiliation center he directs began seeing patients …

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Trial By Error: More on the Perplexing Dutch Claim that Null Results for Objective Measures of Physical Activity Are Irrelevant to Fatigue

By David Tuller, DrPH I recently wrote about a Dutch study published a few months ago in the journal Clinical Infectious Diseases–“Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial.” The study, nick-named ReCOVer, found that unblinded trials relying on subjective outcomes will produce modestly positive reports …

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