Knoop

Trial By Error: More on the Perplexing Dutch Claim that Null Results for Objective Measures of Physical Activity Are Irrelevant to Fatigue

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By David Tuller, DrPH I recently wrote about a Dutch study published a few months ago in the journal Clinical Infectious Diseases–“Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial.” The study, nick-named ReCOVer, found that unblinded trials relying on subjective outcomes will produce modestly positive reports …

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Trial By Error: My Twitter Thread about Slate’s Piece on Long Covid and Mental Illness

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By David Tuller, DrPH Slate recently ran a piece by a young journalist and Stanford neuroscience graduate student, Grace Huckins, about purported links between long Covid and mental illness. I found it problematic. For one thing, in the same sentence it linked to both a story of mine in Codastory.com and one from The Atlantic‘s …

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Trial By Error: Dutch CBT Study for Long Covid Proves that Unblinded Studies with Subjective Outcomes Generate Positive Reports

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By David Tuller, DrPH Three years ago, I wrote a blog post about a problematic Dutch study that had been funded by a major health agency and was being led by Hans Knoop, a professor of medical psychology at Amsterdam University Medical Centers. The study sought to test whether a course of cognitive behavior therapy …

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Trial By Error: The Lancet Publishes Whine de Coeur from Impassioned GET/CBT Defenders

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By David Tuller, DrPH The Lancet has just published an anguished whine de coeur from supporters of the graded exercise therapy/cognitive behavior therapy/ [GET/CBT] approach to ME/CFS. (Or CFS/ME, as these authors insist on calling the illness in what those familiar with the debate will recognize as a childish fit of pique.) These impassioned members …

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Trial By Error: More on the Dutch CBT Long Covid Trial; Finnish Study of “Amygdala Retraining” Program

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By David Tuller, DrPH Update: I have sent the following letter to the responsible person listed on the clinical trial registration for the Finnish study of “amygdala and insula retraining”: Dear Dr Lira– I am a public health researcher and journalist with the Center for Global Public Health, part of UC Berkeley’s School of Public Health. I frequently …

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Trial By Error: Dutch CBT Trial Targets “Dysfunctional Beliefs About Fatigue” in Long Covid Patients

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By David Tuller, DrPH Since the emergence of the phenomenon now called long Covid (or Long COVID, depending on news organization), skeptics have been out in full force. Even as huge numbers of people experience a range of sequelae after a bout of Covid-19, some experts maintain that common non-specific symptoms, like cognitive impairment and …

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