IFN

TWiV 484: Float like a mimivirus STING like a bat

2 Comments / This Week in Virology / By

The TWiVumvirate discuss the giant Tupanvirus, with the longest tail in the known virosphere, and dampened STING dependent interferon activation in bats. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt; Click arrow to play Download TWiV 484 (53 MB .mp3, 87 min) Subscribe (free): iTunes, RSS, email …

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TWiV 450: Ben tenOever and RNA out

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Ben tenOever joins the TWiVoli to discuss the evolution of RNA interference and his lab’s finding that RNAse III nucleases, needed for the maturation of cellular RNAs, are an ancient antiviral RNA recognition platform in all domains of life.   Click arrow to play Download TWiV 450 (58 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show …

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TWiV 382: Everyone’s a little bit viral

This Week in Virology / By

On episode #382 of the science show This Week in Virology, Nels Elde and Ed Chuong join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses. You can find TWiV #382 at microbe.tv/twiv, or listen below. [powerpress …

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TWiV 336: Brought to you by the letters H, N, P, and Eye

This Week in Virology / By

On episode #336 of the science show This Week in Virology, the TWiVsters explore mutations in the interferon pathway associated with severe influenza in a child, outbreaks of avian influenza in North American poultry farms, Ebolavirus infection of the eye weeks after recovery, and Ebolavirus stability on surfaces and in fluids. You can find TWiV …

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