hemagglutinin

There Is No Need to Panic About Bird Flu

by Gertrud U. Rey Public health officials are continuing to monitor the spread of avian H5N1, the strain of influenza virus associated with “bird flu.” Although there is still no evidence that this virus can transmit from one person to another, two recently infected individuals are attracting close attention because the source of their infection …

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TWiV 452: Kiss that frog

Lynda Coughlan joins the weekly virtual bus companions for a discussion of a host defense peptide from frogs that destroys influenza virus, and mouse models for acute and chronic hepacivirus infection. Click arrow to play Download TWiV 452 (68 MB .mp3, 113 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Changing influenza virus neuraminidase into a receptor binding protein

The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins. Apparently this division of labor is not absolute: influenza viruses have been identified with …

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First human infections with avian influenza H7N9 virus

Fourteen people in China have been infected with avian influenza H7N9 virus, leading to five deaths. This avian influenza virus has never been isolated from humans. Influenza A viruses with the H7 hemagglutinin protein circulate among birds, and some, such as H7N2, H7N3, and H7N7, have been previously found to infect humans. It is not known …

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