HCV

TWiV 137: Look what the dog dragged in

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, Amit Kapoor, and Ian Lipkin The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV137.mp3″] Click the arrow above to play, or right-click to download TWiV #137 …

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Canine hepacivirus, a relative of hepatitis C virus

Contemporary human viruses most likely originated by cross-species transmission from non-human animals. Examples include HIV-1, which crossed from chimpanzees to humans, and SARS coronavirus, which originated in bats. Since the 1989 discovery of hepatitis C virus (classified as a hepacivirus in the family Flaviviridae) the origin of the virus been obscure. During the characterization of …

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TWiV 130: Rhino tracking, wrestling pox, and HCV in the crosshairs

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich discuss growth in culture of newly identified rhinovirus C, vaccinia transmission among wrestlers and martial artists, and results of phase III clinical trial of boceprevir, a new inhibitor of hepatitis C virus replication. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV130.mp3″] Click the arrow above to play, or right-click to download …

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TWiV 97: California virology

Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler On episode #97 of the podcast This Week in Virology, Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV097.mp3″] Click …

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TWiV 86: Dark matter with Dr. Eric Delwart

Hosts: Vincent Racaniello, Rich Condit, and Eric Delwart In episode #86 of the podcast This Week in Virology, Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 …

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A new target for hepatitis C virus

When infection with hepatitis C virus goes from acute to chronic, severe liver disease may occur which requires organ transplantation. Nearly 200 million people are chronically infected with HCV, necessitating approaches to preventing and treating infections. No HCV vaccine is available, and current antiviral therapy consists of administration of interferon plus ribavirin, a combination that …

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