FND

Trial By Error: Study Finds “Elevated Brain Injury Markers and Reduced Grey Matter Volume” a Year After Hospitalization for COVID-19

By David Tuller, DrPH A British study of neurological sequelae in patients many months after hospitalization for COVID-19 has found that “post acute cognitive deficits…were associated with elevated brain injury markers in serum and reduced grey matter volume,” according to a pre-print posted earlier this week. (A pre-print is a paper that has not yet …

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Trial By Error: Update on Our Letter Concerning the Prevalence of Functional Neurological Disorder

By David Tuller, DrPH In August, I submitted a letter to NeuroImage: Clinical concerning inflated rates of prevalence of functional neurological disorder, on behalf of myself and nine colleagues. After the letter went through peer review and a round of revisions, I was informed in early November that it had been accepted, as I noted …

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Trial By Error: Letter on Inflated FND Prevalence Rates Accepted for Publication

By David Tuller, DrPH As I have regularly noted, patients with diagnoses of functional neurological disorder (FND) experience tremendous suffering. A patient who goes by the moniker @FnDPortal has written a compelling and sometimes harrowing essay, Cadenza for Fractured Consciousness: A Personal History of the World’s Most Misunderstood Illness, that is well worth a read in …

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Trial By Error: A Follow-Up on a Post About Whether Anxiety and Depression Perpetuate Functional Limb Weakness

By David Tuller, DrPH UPDATE: Physical therapist Zachary Grin, whose criticism prompted this follow-up post, has posted a response, so I have highlighted it right below this introduction. He continues to believe I misrepresented the study. I continue to disagree. Prognostic factors, as he notes, are baseline characteristics. (In this case, “baseline” means mid-illness, so …

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Trial By Error: Depression/Anxiety Not Linked to Negative Outcomes in Patients with Functional Limb Weakness, FND Experts Report

By David Tuller, DrPH The Journal of Psychosomatic Research has just published a paper called “The Impact of Depression, Anxiety and Personality Disorders on the Outcome of Patients with Functional Limb Weakness – Individual Patient Data Meta-Analysis.” As I have previously noted, the journal is something of a house organ for seriously flawed research from …

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Trial By Error: Letter to Journal about Inflated Claims of FND Prevalence

By David Tuller, DrPH I have spent some time trying to correct the record on the reported prevalence of functional neurological disorder (FND). As I have documented, leaders of the FND field have spent the last decade misrepresenting the findings of a seminal 2010 study, Stone et al, to claim that this diagnosis is the …

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