Vincent, Kathy and Rich discuss COVID-19 research paper overload, Moderna’s mRNA vaccine Phase I results, increase of ACE2 RNA by cigarette smoke, and answer listener questions. Click arrow to play Download TWiV 616 (62 MB .mp3, 103 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Nels and Vincent continue their discussion of SARS-CoV-2 evolution, including understanding recurrent mutations in the viral genome, and the potential for re-emergence of the virus from an animal reservoir. Click arrow to play Download TWiEVO 56 (53 MB .mp3, 88 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo
Daniel Griffin provides a clinical update on COVID-19, then we review results showing requirement for the furin site in the SARS-CoV-2 spike for replication, US state vaccine exemptions, concerns with a rapid diagnostic test, and answers to listener questions. Click arrow to play Download TWiV 614 (100 MB .mp3, 167 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! …
The spike glycoprotein of SARS-CoV-2 contains a cleavage site for host cell proteases called furins. Deciphering the role of this cleavage site during infection is important for understanding the origin of the pandemic virus and its disease pattern in humans. Back in February it was not known if the furin site in the SARS-CoV-2 was …
From the authors of Paul Has Measles comes Paul Stays Home, an illustrated book about COVID-19 and SARS-CoV-2 for children. Paul is sad because he can’t go out. He can’t see his friends or visit his grandparents. Like everyone else, he has to wait until the coronavirus pandemic is over. What is the coronavirus? How …
Vincent, Kathy and Rich explain the Jenner Institute’s SARS-CoV-2 vaccine, the NIH decision to stop the Remdesivir study, and answer listener questions. Click arrow to play Download TWiV 613 (63 MB .mp3, 106 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
