The spike glycoprotein of SARS-CoV-2 contains a cleavage site for host cell proteases called furins. Deciphering the role of this cleavage site during infection is important for understanding the origin of the pandemic virus and its disease pattern in humans. Back in February it was not known if the furin site in the SARS-CoV-2 was …
From the authors of Paul Has Measles comes Paul Stays Home, an illustrated book about COVID-19 and SARS-CoV-2 for children. Paul is sad because he can’t go out. He can’t see his friends or visit his grandparents. Like everyone else, he has to wait until the coronavirus pandemic is over. What is the coronavirus? How …
Vincent, Kathy and Rich explain the Jenner Institute’s SARS-CoV-2 vaccine, the NIH decision to stop the Remdesivir study, and answer listener questions. Click arrow to play Download TWiV 613 (63 MB .mp3, 106 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Daniel Griffin provides a weekly clinical update on COVID-19, then Michael Schmidt discusses how dentistry can be safely practiced during a pandemic, followed by answers to listener questions. Click arrow to play Download TWiV 611 (87 MB .mp3, 143 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV!
The TWiV team summarizes serology-based tests for SARS-CoV-2, lack of effect of ACE inhibitors or ARBs on COVID-19 severity, and answers listener questions. Click arrow to play Download TWiV 610 (60 MB .mp3, 99 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission. Click arrow to play Download TWiEVO 55 (45 MB .mp3, 74 min) Subscribe (free): iTunes, Google Podcasts, RSS, email …
TWiEVO 55: Coronavirus evolution from soup to nuts Read More »
