CODES

Trial By Error: New Paper Seeks to Reframe Poor Findings in CODES Trial of CBT for Non-Epileptic Seizures

By David Tuller, DrPH The CODES trial investigated cognitive behavior therapy (CBT) as a treatment for dissociative seizures (DS), a sub-category of what is now called functional neurological disorder (FND). The intervention was a course of CBT specifically designed to address the variety of factors presumed to be triggering the seizures. (I have previously critiqued …

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Trial By Error: My Letter to Author of CODES Commentary

By David Tuller, DrPH Earlier today, I sent the following letter to Dr David Perez, a neurologist and psychiatrist at Massachusetts General Hospital in Boston. Dr Perez, an expert on functional neurological disorders, wrote a commentary for Lancet Psychiatry that accompanied the publication of the results for CODES, a major study of cognitive behavior therapy …

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Trial By Error: CODES Trial Commentary Promotes ‘Eminence-Based Medicine’

By David Tuller, DrPH By all accounts, the recently published CODES trial was the most authoritative study to date of whether cognitive behavior therapy (CBT) was an effective treatment for so-called dissociative seizures–a point confirmed in a commentary accompanying the paper in Lancet Psychiatry. Unfortunately, the CODES investigators and the commentary author seem to interpret …

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