Trial By Error: Revisiting Mahana and Irritable Bowel Syndrome…
…the study’s main analysis of the symptom severity scores used an €œintention-to-treat€ strategy, which tries to account for this sort of missing data. At 12 months, as I have already…
…the study’s main analysis of the symptom severity scores used an €œintention-to-treat€ strategy, which tries to account for this sort of missing data. At 12 months, as I have already…
…out of the longtime suffering of a family member. His account is heartfelt and compelling. Unfortunately, Mr Paull and his company have placed their bets on the wrong horse. I…
…in that study arm, overlooking those who dropped out. In contrast, an intention-to-treat analysis takes into account the fact that some have dropped out of each arm and that their…
…the published account. These practices are critical to prevent what is called selective outcome reporting, when investigators cherry-pick among options to report the most attractive-looking results. All major medical journals…
…to review the reviews, which are appended to the article on the journal’s site. There are major advantages to this system in terms of transparency and accountability. But it can…
…published version offers an account that differs significantly from key trial documents. As is clear from a review of the trial protocol, registration and statistical analysis plan, the research was…