Jonas Salk’s Poliovaccine
Yesterday was the 50th anniversary of the licensing of the first vaccine against poliomyelitis, the inactivated poliovaccine (IPV) developed by Jonas Salk. On 12 April 1955, the results of the…
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Letters from Albert Sabin
The oral poliovirus vaccine (OPV), which has been used to eradicate poliomyelitis in much of the world, was developed by Dr. Albert Sabin during the 1940s and 1950s. This live…
Polio among the Amish
…three states. Twenty years later, use of the live, attenuated poliovirus vaccine (OPV) was discontinued in the United States, and was replaced with the inactivated vaccine, IPV. How do we…
Polio returns to Minnesota
…the infectious, orally administered poliovirus vaccine, OPV. They speculate that the patient was infected with OPV over nine years ago, because the use of this vaccine in the US was…
The rarity of paralysis following poliovirus infection
…recipients of oral poliovirus vaccine). Such an analysis could reinforce the observations made in the study discussed above, or identify variants in different genes that predispose vaccine recipients to VAPP….
SARS-CoV-2 variants of concern
…the virus particle, and specifically the spike protein for those given the mRNA vaccine. Some of the spike changes identified in variants are in regions known to bind antibodies. Consequently…