Defective viral genomes and severe influenza
…mild or severe influenza. In cell culture, isolates from cases of severe influenza produced ten times less defective RNA than isolates from mild cases. However, the mutations in these isolates…
Search Results for: influenza vaccine
Herd Immunity
…population that is immune. However, spread of vaccine is not the concept embodied by herd immunity. The vaccine against smallpox, called vaccinia virus, is a live vaccine and also spreads…
Dreaming of inactivated poliovirus vaccine
…might not be possible. Twenty-one cases of paralytic polio were caused by a vaccine-derived poliovirus strain (VDPV). Although it had been known since the 1960s that vaccine viruses excreted by…
Would we have an Ebola virus vaccine if not for NIH cuts?
…be ready by now is overly optimistic. Vaccines are not easy to design, as the efforts to make an HIV-1 vaccine illustrate. There is no guarantee that even unlimited resources…
Antibodies to dengue virus enhance infection by Zika virus
…induced by this vaccine make Zika virus disease more severe? This outcome would be a tragedy, as many years of work has gone into making this vaccine to prevent severe…
HPV vaccines do not encourage risky sexual behavior
The human papillomavirus (HPV) vaccines save lives by preventing lethal cervical and anogenital cancers. If Henrietta Lacks had received an HPV vaccine, she would not have succumbed to cervical…