How herpes simplex virus exits latency
Many of us have experienced herpesvirus reactivation from latency. Suddenly a sore erupts on the lip, festers for a week, then subsides. Years later, for no apparent reason, it happens…
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Poliovirus vaccine litigation
…live, oral trivalent poliovirus vaccine previously produced by Lederle Laboratories). Approximately 6 weeks later, the plaintiff developed severe back pain and then permanent paralysis of both legs. I will focus…
Should we be worried about monkeypox?
…is caused by varicella-zoster virus (a herpesvirus, unrelated to poxviruses). However, unlike chickenpox lesions, which can individually exist in different stages of development throughout the course of infection, monkeypox lesions…
100th anniversary of the isolation of poliovirus
…animals intraperitoneally. The Cynocephalus monkey succumbed eight days later… The real test came when histological sections of the spinal cord revealed typical and extensive lesions which had a remarkably close…
TWiP 14: Leishmania
…braziliensis life cycle (jpg) L. donovani life cycle (jpg) L. tropica life cycle (jpg) L. major lesion (jpg) Transgenic mosquito delivers Leishmania vaccine (thanks, Geoffrey) Plasmodium falciparum accompanied human expansion…
Trial By Error: Professor Jonathan Edwards’ View of ME
…later, having been asked to advise on immunological research. As a practicing doctor I thought that there are many causes of fatigue, some known, some not, but that we did…