Poliovirus
…developed in the 1950s that can effectively prevent the disease – inactivated poliovaccine (IPV, developed by Jonas Salk) and live, oral poliovaccine (OPV, developed by Albert Sabin). In 1988 the…
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Poliovirus is IRESistable
…recent paper we show that this is not the case. The other topic of our paper concerns the live poliovirus vaccine, also known as the Sabin vaccine or oral poliovirus…
Letters from Albert Sabin
The oral poliovirus vaccine (OPV), which has been used to eradicate poliomyelitis in much of the world, was developed by Dr. Albert Sabin during the 1940s and 1950s. This live…
Dreaming of inactivated poliovirus vaccine
The World Health Organization’s global polio eradication effort uses the live, attenuated poliovirus vaccines developed by Albert Sabin. When the eradication program was announced in 1988, the goal was to…
Polio among the Amish
…three states. Twenty years later, use of the live, attenuated poliovirus vaccine (OPV) was discontinued in the United States, and was replaced with the inactivated vaccine, IPV. How do we…
Bacteriophages, viral vaccines, and poliovirus
…is contaminated with bacteriophages, which are not removed when the serum is sterilized by filtration. When bacteriophages were discovered in live viral vaccines in the 1970s, a controversy ensued –…