Ebola virus glycoprotein antagonizes tetherin
…to the plasma membrane in order to exert its anti-tetherin activity. It will be of great interest to determine how Ebola virus GP and proteins of other viruses permit virion…
Search Results for: day 501 virus school
Did smallpox lead to HIV-1 resistance?
…human viral infection: smallpox. Myxoma virus, a member of the poxvirus family, causes lethal disease in rabbits. Mouse cells that cannot be infected by this virus can be made susceptible…
Early Immune Responses to Herpes Simplex Virus Type I Infection
by Gertrud U. Rey Herpes simplex viruses infect cells of the skin and mucous membranes, where they establish a lifelong persistent infection in sensory neurons. Sporadic reactivation and viral shedding…
A Universal Antiviral Drug
…stomatitis virus, influenza virus, West Nile virus, and SARS-CoV-2 (the virus that causes COVID-19) in cell culture. To see whether this effect also occurs in animals, the authors generated a…
The Route Matters
…IgA mediates elimination of pathogens that have breached the mucosal surface. Several of the SARS-CoV-2 vaccine candidates currently in clinical trials consist of a replication-deficient adenovirus with an inserted gene…
Why We Can’t Eradicate Polio
…“vaccine-derived viruses” in the environment is particularly problematic in under-immunized populations, where the viruses circulate and cause outbreaks identical to those caused by wild-type poliovirus. In rare cases, the attenuated…