Search Results for: Trial by Error

…similarities between PACE and the Dutch FITNET trial on which it is based. Like the PACE trial, the Dutch relied on a post-hoc definition of recovery. The thresholds the FITNET…

…his open letters. PACE was a poorly designed and executed clinical trial. Racaniello added this: The PACE trial illustrates exactly how NOT to conduct a clinical trial. My Columbia colleague,…

…not, why not? A biostatistics professor from Columbia told me that for investigators to publish such information during a trial was “the height of clinical trial amateurism,” and that at…

…with problems of systemic bias in trial execution.” Studies with this design, he explained, have been abandoned in other fields of medicine. The difficulty of shielding such trials from systematic…

…research misconduct since I started my PACE investigation. In my long Virology Blog series in October 2015, I decided to document the trial’s extensive list of flaws, or as many…