…trial with more than 500 participants. Unfortunately for the investigators, the trial essentially demonstrated the program’s ineffectiveness. To begin with, the trial was an unblinded study relying on self-reported outcomes,…
By David Tuller, DrPH It’s been ten years since The Lancet published the first results of the PACE trial. Wow! Ten years ago, I was 54 and still a graduate…
By David Tuller, DrPH The Journal of Psychosomatic Research (JSR), an influential publication. recently published an article that made a crucial point, in clinical trials, subjective outcomes are at “a…
…and disparaging patient advocacy groups, Devine asserted that the PACE trial’s psychogenic theory of ME/CFS is “the prevailing view among medical practitioners.” As readers of this site know, that has…
…Disease 2019: Results of a Randomized Controlled Trial.” The study, nick-named ReCOVer, found that unblinded trials relying on subjective outcomes will produce modestly positive reports in the group receiving the…
By David Tuller, DrPH *This is a crowdfunding month at UC Berkeley for my Trial by Error project. If you appreciate my work and would like to help support it, here’s…
