…trial in which participants who did not receive the specialized seizure-reduction intervention showed a (not statistically significant) trend toward more improvement on the primary outcome than those who did receive the intervention. …
…in a fully powered randomised controlled trial.” Given the poor outcome results, why would they conduct a follow-up trial? Why would anyone provide them with more funding when they have…
…trial with more than 500 participants. Unfortunately for the investigators, the trial essentially demonstrated the program’s ineffectiveness. To begin with, the trial was an unblinded study relying on self-reported outcomes,…
By David Tuller, DrPH It’s been ten years since The Lancet published the first results of the PACE trial. Wow! Ten years ago, I was 54 and still a graduate…
By David Tuller, DrPH The Journal of Psychosomatic Research (JSR), an influential publication. recently published an article that made a crucial point, in clinical trials, subjective outcomes are at “a…
…and disparaging patient advocacy groups, Devine asserted that the PACE trial’s psychogenic theory of ME/CFS is “the prevailing view among medical practitioners.” As readers of this site know, that has…
