Viral quasispecies and bottlenecks
…the population. Error-prone replication ensures that the members of the new population have many other mutations in their genomes. The type of population selection illustrated above most likely took place…
Search Results for: Trial by Error
Influenza A/Mexico/2009 (H1N1) virulence and transmission
…reference to a ‘molecular clock’ in the previous paragraph, having read previous posts on the error-prone nature of RNA virus replication. These approaches allow an estimation of the onset of…
Influenza 101
…influenza virus neuraminidase Release of influenza viral RNA into cells Influenza HA cleavage is required for infectivity RNA Synthesis Influenza viral RNA synthesis The error-prone ways of RNA synthesis The…
Reassortment of the influenza virus genome
Mutation is an important source of RNA virus diversity that is made possible by the error-prone nature of RNA synthesis. Viruses with segmented genomes, such as influenza virus, have another…
Detecting viruses: the plaque assay
…units (PFU) per milliliter. To determine the virus titer, the plaques are counted. To minimize error, only plates containing between 10 and 100 plaques are counted, depending on the size…