Could the Ebola virus epidemic have been prevented?
…primates with Ebola virus, it is not known if it would work in humans. Answering that question requires a clinical trial, and the article explores why this phase was not…
Search Results for: Trial by Error
B cell depletion benefits ME/CFS patients
…severe fatigue, post-exertional malaise, pain, cognitive and sleep problems that affects 0.1-0.2% of the population. A previous randomized, phase II trial of rituximab treatment showed clinical benefit in 20 of…
A problem with dengue virus vaccine
…the virus. The results of a phase 3 clinical trial indicated that immunization protected not only against primary infection, but also against severe disease. Dengvaxia was licensed based on data…
A Statement in Support of Cochrane
…are open label trials relying on subjective outcomes. Trials with this design are fraught with bias, which is why they are no longer considered as reliable evidence for making decisions…
SARS-CoV-2 – The vaccine landscape
…escalated development and sent vaccine to NIAID to begin the process of initiating a phase I trial to test the safety and immunogenicity of the vaccine. The trial is projected…
Hydroxychloroquine reduces viral load in COVID-19 patients
…small clinical trial has revealed it to be effective in reducing viral loads in COVID-19 patients. Entry of enveloped viruses into cells requires fusion of viral and cell membranes to…