The number of possible viral variants
…in an infected individual appear to be nonviable, suggesting that the population exists at its error threshold. What would happen if we could push replicating genomes over the error threshold?…
Search Results for: Trial by Error
Viroids, infectious agents that encode no proteins
…molecules that catalysed their own synthesis. Viroids have properties that make them candidates for survivors of the RNA world: small genome size (to avoid error catastrophe caused by error-prone replication),…
New influenza antiviral drugs
…This property is useful for controlling outbreaks in communities and institutions. Daiichi Sankyo Co. started a Phase III trial for adults and a pediatric Phase II/III trial with CS-8958 in…
Anti-HIV ribozyme: an alternative to HAART?
…viral resistance are continuing problems. Is there an alternative for AIDS patients? The results of a phase 2 gene therapy trial suggest that gene therapy with an anti-HIV ribozyme could…
Single dose of 2009 H1N1 vaccine immunogenic in adults
An Australian group has reported results of a clinical trial to determine the safety and immunogenicity of a 2009 pandemic H1N1 influenza virus vaccine. Twenty-one days after the first of…
TWiP 31: A malaria vaccine
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children. [powerpress url=”http://traffic.libsyn.com/twip/TWiP031.mp3″] Click the arrow…