Search Results for: Trial by Error

…design a trial. He claims the SMILE trial’s results also undermine the PACE trial €“ which also used an unblinded trial with subjective outcomes €“ by showing that “the same…

…observation was not known to clinical triallists in 2004, but it was. At the time PACE was being planned I was publishing my proof of concept trial for rituximab in…

…subsequent essay called “The PACE Trial: A Catalogue of Errors”: “The PACE Trial team were operating within a closed system or groupthink in which they ‘know’ their theory is correct….

…otherwise have been possible. The changes are only apparent from a review of other documents, such as the trial registration, the feasibility trial protocol and the full-trial protocol. My specific…

…back and retroactively correct this glaring lack of pre-trial disclosure. One participant was so upset at finding out about these insurance industry links after she had already completed the trial…