Q&A with A&V Livestream 4/13/22

Virologists Amy Rosenfeld and Vincent Racaniello answer your COVID-19 questions (or any virus questions) on this livestream of 4/13/22 at 8:30 PM eastern US.

TWiV 887: Bonfire of the monocytes

TWiV explains why this season's influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19.

TWiV 886: COVID-19 clinical update #109 with Dr. Daniel Griffin

In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine dose in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity.

A Viral Risk Factor for Multiple Sclerosis

Several new lines of evidence suggest that Epstein-Barr virus infection may be a risk factor for the development of multiple sclerosis.

TWiV 885: Russian bats and Ankara vectors

TWiV reveals an ACE2-dependent sarbecovirus from Russian bats that is not inhibited by anti-SARS-CoV-2 antibodies, and a modified vaccinia virus Ankara vectored vaccine that protects nonhuman primates from Delta infection.

Q&A with A&V Livestream 4/6/22 

Virologists Amy Rosenfeld and Vincent Racaniello answer your COVID-19 questions (or any virus questions) on this livestream of 4/6/22 at 8:30 PM eastern US.

Trial By Error: Cochrane Continues Telling ME/CFS Patients to Go F–k Themselves

By David Tuller, DrPH Update/Correction: Below, I initially wrote that Cochrane was lying in describing the update plan as a “pilot project.” However, it turns out that the organization did describe its plan to engage community partners as a “pilot project.” Here’s the statement from March, 2020: “Cochrane is conducting a pilot project for engaging …

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Trial By Error: Cochrane Tells ME/CFS Patients to Go F–k Themselves

By David Tuller, DrPH Cochrane has just given the finger to the international ME/CFS community. After jerking everyone around and promising for five years to conduct a new review of exercise interventions for the illness, the organization abruptly abandoned that commitment this week. On Monday, Cochrane posted the following message on its website: “In 2019, …

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Trial By Error: Agencies Respond to Coroner’s Report in Boothby O’Neill Inquest

Update: Maeve’s mum, Sarah Boothby, has commented on this blog. I am posting her comment here: Sorry if this seems picky but Maeve did not die in hospital [DT: Fixed! Not sure how I made this error] and the RDUH Trust document is what we call a treatment pathway. It is the first of its …

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Trial By Error: Letter to BMJ Editor Seeking Correction in New Review of Interventions for Long Covid

By David Tuller, DrPH The BMJ recently published a review of interventions for Long Covid that–surprise!–recommended CBT and a rehabilitation program as treatments. The review is full of holes. I have focused on one in particular. The review relies for its rehabilitation recommendation on an earlier BMJ study–even though that study has itself already been …

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Trial By Error: Yet Again BMJ Recommends CBT and Exercise for Long Covid

By David Tuller, DrPH What is going on at The BMJ? In May, the journal corrected an obvious error in a paper about a prominent Long Covid mental and physical rehabilitation trial called REGAIN. The trial was conducted among patients who had been hospitalized for Covid-19, but key sections of the paper generalized the findings …

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Trial By Error: Canadian Group Seeks Feedback on Recommendations for Exercise and CBT for Long Covid

By David Tuller, DrPH A group called Canadian Guidelines for Post COVID-19 Condition (CAN-PCC) has released a new set of draft recommendations related to preventing, diagnosing and treating what is commonly called Long Covid. The current list of nine draft recommendations includes exercise and cognitive behavior therapy, which has understandably raised concerns among advocates for …

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