David Tuller
Trial By Error: A Letter Seeking a Correction in FMD Physiotherapy Paper
By David Tuller
By David Tuller, DrPH I have recently written about a trial of an intervention for functional motor disorder (FMD) that had null results for its primary outcome—physical function as rated by the SF-36. The study--"Specialist Physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 ...
Trial By Error: When Primary Outcomes Yield Null Results in Clinical Trials, FND Experts Prefer Their Secondary Outcomes
By David Tuller
By David Tuller, DrPH In 2020, the CODES study of cognitive behavior therapy (CBT) for psychogenic non-epileptic seizures, also known as dissociative seizures, reported null findings for its primary outcome—the number of seizures per month one year after the start of therapy. This was a disappointing result for an ambitious ...
Trial By Error: Australian GPs Keep Promoting Exercise Treatments for ME/CFS
By David Tuller
By David Tuller, DrPH When it comes to treatments for ME/CFS, the Royal Australian College of General Practitioners (RACGP) has long endorsed the graded exercise therapy (GET)/cognitive behavioral therapy (CBT) approach. Last April, the organization published an “updated” article in its Handbook of Non-Drug Interventions (HANDI) advocating “incremental physical activity” ...
Trial By Error: Andrew Ewing & David Joffe on Just-Published “Global Expert Consensus” on Long Covid
By David Tuller
By David Tuller, DrPH *This is a crowdfunding period at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 Last week, the journal Annals of Clinical Microbiology and ...
Trial By Error: #MEAction’s Jaime Seltzer on Where We’ve Been, What We’ve Learned, and Where Things Are Now
By David Tuller
By David Tuller, DrPH *This is a crowdfunding period at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 It's been five years, more or less, since the ...