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No ‘Recovery’ in PACE Trial, New Analysis Finds

Last October, Virology Blog posted David Tuller’s 14,000-word investigation of the many flaws of the PACE trial (link to article), which had reported that cognitive behavior therapy and graded exercise therapy could lead to “improvement” and recovery from ME/CFS. The first results, on “improvement,” were published in The Lancet in 2011; a follow-up study, on …

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TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids. You can find TWiV #406 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV406.mp3″] Click arrow to play Download TWiV 406 (59 MB .mp3, 98 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!

Open letter to Queen Mary University of London about PACE

Professor Simon Gaskell President and Principal Queen Mary University of London Mile End Road London E1 4NS Dear Professor Gaskell: Last month, the First-Tier Tribunal ordered Queen Mary University of London to release critical data from the PACE trial of treatments for chronic fatigue syndrome, also known as myalgic encephalomyelitis, or ME/CFS. In its decision, …

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Trial By Error, Continued: My Questions for Lancet Editor Richard Horton

By David Tuller, DrPH In January, I posted a list of the questions I still wanted to ask the PACE authors, who have repeatedly refused my requests to interview them about their ethically and methodologically challenged study. Richard Horton, editor of The Lancet, has similarly declined to talk with me, ignoring my e-mails seeking comment …

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Once Again, Lancet Stumbles on PACE

Last February, Virology Blog posted an open letter to The Lancet and its editor, Dr. Richard Horton, describing the indefensible flaws of the PACE trial of treatments for ME/CFS, the disease otherwise known as chronic fatigue syndrome (link to letter). Forty-two well-regarded scientists, academics and clinicians put their names to the letter, which declared flatly …

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TWiV 403: It’s not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine. You can find TWiV #403 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV403.mp3″] Click arrow to play Download TWiV 403 (70 MB .mp3, 96 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV!