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Trial By Error: My Letter to LP Study’s Senior Author

By David Tuller, DrPH Alan Montgomery is a professor of medical statistics and clinical trials at the University of Nottingham€™s School of Medicine. He is also the senior author of the Lightning Process study published in 2017 in Archives of Disease in Childhood, a BMJ journal. Professor Montgomery formerly worked at University of Bristol, along …

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Trial By Error: “Talk is Cheap,” Patients Tell NIH

By David Tuller, DrPH Earlier this month, NIH director Francis Collins and other agency officials held a meeting with five representatives from #MEAction. According to the group’s post about the meeting, the goal was to discuss accelerating research in order to more rapidly provide diagnostics and treatments to people with ME. Specifically, #MEAction urged the …

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Trial By Error: Australian Draft Report Seeks Comments

By David Tuller, DrPH In an eagerly awaited draft report, an Australian advisory committee on ME/CFS has called for the development of up-to-date domestic clinical guidelines and an increase in biomedical research into the pathophysiology of the illness. The draft report, which could have a major impact on health policy going forward, also highlights the …

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An inborn error of innate immunity leading to severe rhinovirus infections

When a human population is exposed to a pathogenic virus, the outcomes among individuals may include asymptomatic, mild, severe, or no infection. Multiple parameters control these responses, including the amount of virus taken up, the age of the host, general health status, nutrition, and more. With the advent of whole exome sequencing we can now …

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