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Trial By Error: Letter to BMJ Paediatrics Open About that CBT-Music Therapy Study

By David Tuller, DrPH UPDATE: I sent the following correction to Dr Choonara shortly after sending the letter of concern. Dear Dr Choonara: I wanted to make a slight correction in point #3 below. The first sentence should have read: “Why was the outcome of recovery not mentioned in the trial registration and statistical analysis …

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A mouse model for COVID-19

Small animal models (mice, ferrets, hamsters) are essential for understanding how SARS-CoV-2 causes disease and for pre-clinical evaluation of vaccines and antiviral therapeutics. One promising model has been developed by modifying SARS-CoV-2 so that it binds to murine ACE2. Laboratory mice cannot be infected with SARS-CoV-2 because the viral spike glycoprotein (illustrated) does not bind …

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Trial by Error: Tack’s Take on BMJ’s CBT-Music Therapy “Feasibility Study”

By David Tuller, DrPH I have always made it clear that I pay attention when smart patients assess bad research. That’s how I stumbled into this whole mess in the first place–by reading what patients were writing about the PACE trial. (In that case, I at first dismissed the concerns when I read about how …

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Trial By Error: My Letter to Peer Reviewer of BMJ’s CBT-Music Therapy Paper

By David Tuller, DrPH I have recently written a few posts–here, here and here–about a study in BMJ Paediatrics Open that appears to be marred by multiple methodological and ethical problems. This is certainly not a one-time occurrence when it comes to BMJ journals. Last week, I sent a letter to the study’s senior author inviting him to …

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Trial By Error: My Letter to Senior Author of Norway’s CBT-Music Therapy Study

By David Tuller, DrPH In the past week, I have written three posts about a Norwegian study of cognitive behavior therapy plus music therapy for adolescents with chronic fatigue after acute Epstein-Barr virus infection–an illness known as mononucleosis in the US and glandular fever in the UK. The corresponding author of the study is Vegard …

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