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Trial By Error: NIH Funding “Needs Life Support,” Says Jennie Spotila

By David Tuller, DrPH Every year, Jennie Spotila deconstructs NIH funding on her Occupy M.E. blog. Last November 7, she crunched the numbers for the 2019 fiscal year, and the same day posted another blog with a more urgent message. I am re-posting that blog in full (a bit late), with Jennie’s permission. ********** NIH Funding …

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Trial By Error: The Danish ME Association’s Open Letter

By David Tuller, DrPH The Danish ME Association has sent and posted the following open letter to “Danish health politicians,” with a very impressive list of international signatories. It seemed important to give this letter wide circulation. (Note that footnotes 4 and 5 are linked to the names of two of the signatories, as in …

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Trial By Error: My 2011 Exchange with White et al about Case Definition

By David Tuller, DrPH My first exchange of views with the PACE authors involved the issue of case definition–the criteria used to identify the illness they  called chronic fatigue syndrome. This exchange took place courtesy of The New York Times, not long after The Lancet published the results of the PACE trial. In March, 2011, …

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Trial By Error: PEM Is Bad and So Is Fukuda, New Study Finds

By David Tuller, DrPH A new study in the Journal of Psychosomatic Research, posted December 16th, has reported that patients with chronic fatigue syndrome who experience major post-exertional malaise have a greater burden of psychological distress than those whose PEM is minimal or non-existent. Of course, this is not surprising. The sicker people are, with …

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Antibiotics blunt the antibody response to influenza vaccine

The human gut microbiome appears to play diverse roles in host physiology, metabolism, and immunity. Most conclusions about what the trillions of bacteria in our intestines actually do come from studies in mice, or correlative studies in humans. An exception is an investigation in humans which shows that antibiotic-mediated alteration of the fecal microbiome* interferes …

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Trial By Error: My STAT Opinion Piece on BMJ and Dr Godlee

By David Tuller, DrPH On Friday, STAT posted my opinion piece about BMJ and the Lightning Process paper–in particular, about BMJ’s decision not to retract the paper despite the multiple documented violations of core ethical and methodological principles of medical research. That anti-scientific decision is potentially harmful not only to children suffering from a stigmatizing …

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