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The human gut microbiome appears to play diverse roles in host physiology, metabolism, and immunity. Most conclusions about what the trillions of bacteria in our intestines actually do come from studies in mice, or correlative studies in humans. An exception is an investigation in humans which shows that antibiotic-mediated alteration of the fecal microbiome* interferes …

Antibiotics blunt the antibody response to influenza vaccine Read More »

By David Tuller, DrPH On Friday, STAT posted my opinion piece about BMJ and the Lightning Process paper–in particular, about BMJ’s decision not to retract the paper despite the multiple documented violations of core ethical and methodological principles of medical research. That anti-scientific decision is potentially harmful not only to children suffering from a stigmatizing …

Trial By Error: My STAT Opinion Piece on BMJ and Dr Godlee Read More »

By David Tuller, DrPH Simon McGrath provides excellent accounts of research topics at his blog, ME/CFS Research Review. He is skilled at rendering complicated stuff into easy-to-understand prose. On December 10th, Simon posted this update of developments discussed by Stanford geneticist Ron Davis during a recent talk at the Albert Einstein College of Medicine in New …

Trial By Error: Simon McGrath on Ron Davis on “something in the blood” Read More »

By David Tuller, DrPH What’s going on at the Mayo Clinic? It has been more than two years since the US Centers for Disease Control and Prevention (CDC) removed cognitive behavior therapy and graded exercise therapy as treatments of choice for the illness it now calls ME/CFS. And Mayo still seems not to have noticed …

Trial By Error: Mayo Clinic’s Crappy Website Read More »

By David Tuller, DrPH Last last month, I resent Dr Fiona Godlee a letter criticizing BMJ’s decision to republish the Lightning Process study with the same findings. The first iteration, in July, was signed by 55 scientists, clinicians and other experts. This version was signed by more than 70 experts and over 60 patient and …

Trial By Error: More Calls to Godlee for LP Study Retraction Read More »

By David Tuller, DrPH In July, I sent Dr Fiona Godlee, editorial director of BMJ, a letter signed by 55 experts about her company’s perplexing decision to republish the originally reported–and unreliable–findings from the trial of the Lightning Process. She did not respond. This morning I sent the letter again, with more individual signatories along …

Trial By Error: Open Letter to Dr Godlee about BMJ’s Ethically Bankrupt Actions (2) Read More »