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Trial By Error: Study Finds “Elevated Brain Injury Markers and Reduced Grey Matter Volume” a Year After Hospitalization for COVID-19

By David Tuller, DrPH A British study of neurological sequelae in patients many months after hospitalization for COVID-19 has found that “post acute cognitive deficits…were associated with elevated brain injury markers in serum and reduced grey matter volume,” according to a pre-print posted earlier this week. (A pre-print is a paper that has not yet …

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Trial By Error: Dutch Study Links PEM in Long Covid to Biological Abnormalities

By David Tuller, DrPH A new study in Nature Communications, called “Muscle abnormalities worsen after post-exertional malaise in long COVID,” caused a stir after it was published last week. The investigators identified significant biological differences after an exercise challenge between long Covid (LC) patients with post-exertional malaise (PEM) and matched healthy controls who had recovered …

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Trial By Error: Update on NICE Response to “Anomalies” Paper; Higher ME/CFS Population Estimates in CDC Survey

By David Tuller, DrPH Update: In the comments, Colleen Steckel has highlighted her concerns about the CDC prevalence data, writing: “There is some basic misinformation in the CDC survey reporting. The results need to be put into historical perspective. Repeating narratives, based on inaccurate information, are not helping people with ME get recognized.” You can …

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Trial By Error: Disastrous Results for Professor Crawley’s Pediatric Online CBT Trial

By David Tuller, DrPH Pediatrician Esther Crawley, Bristol University’s methodologically and factually challenged grant magnet, has released what seem to be the first outcome results from her much-hyped but fatally flawed FITNET-NHS trial—and they are disastrous. The trial, a pediatric study of online CBT based on similar Dutch research that (falsely) claimed to have proven …

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Trial By Error: Julie Rehmeyer on the Heartbreaking Loss of Beth Mazur

By David Tuller, DrPH Beth Mazur was a long-time ME advocate and a co-founder of #MEAction. ME-world was shocked to learn on Friday–two days ago–that she was gone, at the unconscionably young age of 47. At the time, she was visiting New Mexico and Julie Rehmeyer, another patient and advocate. Words often fail at times …

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