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Trial By Error: Letter on Inflated FND Prevalence Rates Accepted for Publication

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By David Tuller, DrPH As I have regularly noted, patients with diagnoses of functional neurological disorder (FND) experience tremendous suffering. A patient who goes by the moniker @FnDPortal has written a compelling and sometimes harrowing essay, Cadenza for Fractured Consciousness: A Personal History of the World’s Most Misunderstood Illness, that is well worth a read in …

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Trial By Error: What’s Going On with Cochrane’s Exercise Review Mess?

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By David Tuller *This post has been corrected. In the first sentence, I originally wrote in error that the open letter was sent to Cochrane on September 4th, not on August 28th. On August 28th, the Science for ME (S4ME) forum sent an open letter to Cochrane’s editor-in-chief, Karla Soares-Weiser, requesting the “immediate withdrawal or …

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Trial By Error: A Crap Study on “Psychosomatic Therapy” for “Persistent Somatic Symptoms”

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By David Tuller, DrPH *This post has been corrected. I initially wrote that the protocol did not appear to call for sub-group analyses, but in fact it did. The post also includes a passage that is from documentation in the supplemental material, but I had identified it as coming from the protocol. I apologize for …

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Trial By Error: A Follow-Up on a Post About Whether Anxiety and Depression Perpetuate Functional Limb Weakness

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By David Tuller, DrPH UPDATE: Physical therapist Zachary Grin, whose criticism prompted this follow-up post, has posted a response, so I have highlighted it right below this introduction. He continues to believe I misrepresented the study. I continue to disagree. Prognostic factors, as he notes, are baseline characteristics. (In this case, “baseline” means mid-illness, so …

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Trial By Error: Depression/Anxiety Not Linked to Negative Outcomes in Patients with Functional Limb Weakness, FND Experts Report

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By David Tuller, DrPH The Journal of Psychosomatic Research has just published a paper called “The Impact of Depression, Anxiety and Personality Disorders on the Outcome of Patients with Functional Limb Weakness – Individual Patient Data Meta-Analysis.” As I have previously noted, the journal is something of a house organ for seriously flawed research from …

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Trial By Error: Authors of Dutch Long Covid Paper Contradict Each Other

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By David Tuller, DrPH I have slammed a recent Dutch study, Kuut et al, that investigated CBT for fatigue after an acute bout of COVID-19. The study, “Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial,” nicknamed ReCOVer, was published in Clinical Infectious Diseases, a well-regarded journal, …

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