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TWiV 32: Influenza in silico

On episode #32 of the podcast This Week in Virology, Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV032.mp3″] Click the arrow above to play, or right-click to download TWiV #32 or subscribe in iTunes or by email.

Influenza A/Mexico/2009 (H1N1) virulence and transmission

The influenza H1N1 outbreak in Mexico has been analyzed to provide information on the pandemic potential of the new virus strain. The estimates offer some insight into the transmissibility and severity of the virus but must be tempered with the understanding that there are still uncertainties about all aspects of the outbreak. Influenza incidence is …

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Influenza virus RNA: Translation into protein

Let’s resume our discussion of the influenza virus genome. Last time we established that there are eight negative-stranded RNAs within the influenza virion, each coding for one or two proteins. Now we’ll consider how proteins are made from these RNAs. Figure 1 shows influenza RNA segment 2, which encodes two proteins: PB1 and PB1-F2. The …

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Influenza A/Mexico/2009 (H1N1): Questions and answers

Here are my answers to questions about the currently circulating influenza H1N1 strain (formerly swine flu) sent by readers of virology blog. A reader from Mexico shared the following numbers with virology blog, then asked a question about hog cholera. Q: There are 312 confirmed cases of swine virus here in Mexico and 12 of …

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