In this week’s discussion of swine flu A/Mexico/09 (H1N1), we have considered many aspects of influenza virus biology that might not be familiar to some readers of virology blog. I thought it might be useful to explain how the virus multiplies, how it infects us, and how we combat infection. Today we’ll start with the …
The isolates of influenza virus obtained in the current global outbreak have proven to be resistant to the adamantane antivirals, but susceptible to oseltamivir (Tamiflu) and zanamivir (Relenza). Consequently the two neuraminidase inhibitors will likely be used extensively to control the outbreak until a vaccine is available. Extended use of the antiviral drugs will undoubtedly …
Oseltamivir resistance decreases influenza aerosol transmission Read More »
Here is an update on the global swine flu situation as of 29 April 2009. Not surprisingly, laboratory confirmed case counts continue to rise globally. There are 91 cases in the US in 10 states (Arizona, California, Indiana, Kansas, Massachusetts, Michigan, Nevada, New York, Ohio, Texas). There has been a laboratory confirmed fatal case in …
Here are my answers to questions about swine flu sent by readers of virology blog: Q: Can you please tell me why there is a flu “season”. Influenza is seasonal in temperate climates because conditions found during winter, low temperature and humidity, favor spread of the infection. In the dry conditions of winter, virus-laden respiratory …
Here is an update on the global swine flu situation as of 28 April 2009. There are now 64 laboratory confirmed cases of infection with the H1N1 swine influenza strain, up from 40 the day before. States reporting cases are California (10), Kansas, (2), New York City (45), Ohio (1) and Texas (6). These are …
I have received several questions about my assertion that the northern hemisphere is safe, at least until the fall, from an epidemic of A/California/09/2009 influenza virus. Here are two representative questions: If I recall correctly, Spanish flu hit hardest during the summer and fall. As for the swine flu, is it impossible (and why?) to …
Swine influenza, seasonality, and the northern hemisphere Read More »
