Virology lecture #5: Attachment and entry
Download: .wmv (386 MB) | .mp4 (131 MB) There are some errors in this lecture – I’ll correct them during the next session. Visit the virology W3310 home page for a complete list of course resources.
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Now playing: Viral plaque formation
One of the most important procedures in virology is measuring the virus titer €“ the concentration of viruses in a sample. A widely used approach for determining the quantity of infectious virus is the plaque assay. In this technique, the spread of progeny viruses released by individually infected cells is restricted to neighboring cells by …
XMRV infection is enhanced by prostatic protein fragments
Fragments of an abundant protein produced by the prostate form amyloid fibrils that enhance infection of cells by human immunodeficiency virus type 1. These fibrils, called semen-derived enhancer of virus infection (SEVI), have been found to boost infection of prostate cells by the retrovirus XMRV. Is this evidence that XMRV causes prostate cancer? Because most …
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Koch’s postulates in the 21st century
For thousands of years, epidemics of contagious diseases were believed to be caused by the wrath of the gods, configuration of stars, or miasma. The association of specific microorganisms with disease came about as a consequence of the work of the German physician Robert Koch. He formulated a set of criteria that could be used …
A new virology course at Columbia University
Tomorrow is the start of my new virology course at Columbia University. The course, Biology W3310, is aimed at advanced undergraduates and will be taught at the Morningside Campus of Columbia University. Columbia University encompasses two principal campuses: the historic, neoclassical campus in the Morningside Heights neighborhood and the modern Medical Center further uptown, in …
Radio Sandy Springs interview
I was recently interviewed on Radio Sandy Springs by Sharon Sanders of FluTrackers. We talked about pandemic influenza H1N1 virus. Listen to the show below. [audio:https://www.virology.ws/InfectiousDiseaseJan042010.mp3 | titles=Infectious Disease Hour] Download Infectious Disease Hour January 4 2010 (20 MB .mp3, 57 minutes) Radio Sandy Springs 1620 AM is a low-powered Atlanta-based talk radio station that …