Basic virology

XMRV not found in 170 additional UK chronic fatigue syndrome patients

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A new retrovirus, xenotropic murine leukaemia virus-related virus (XMRV), first identified in tumor tissue of individuals with prostate cancer, was subsequently found in 68 of 101 US patients with chronic fatigue syndrome (CFS). XMRV was not detected in blood samples of 186 confirmed CFS patients in the United Kingdom. A second independent study in the …

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Protection against 2009 influenza H1N1 by immunization with 1918-like and classical swine viruses

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Influenza A viruses typically cause severe respiratory disease mainly in the very young or the elderly. The 2009 swine-origin H1N1 virus is unusual because it preferentially infects individuals under 35 years of age. We’ve previously noted that being older is a good defense against 2009 H1N1 influenza virus, in part because older people have antibodies that …

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Now playing: Viral plaque formation

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One of the most important procedures in virology is measuring the virus titer €“ the concentration of viruses in a sample. A widely used approach for determining the quantity of infectious virus is the plaque assay. In this technique, the spread of progeny viruses released by individually infected cells is restricted to neighboring cells by …

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