Basic virology

XMRV, prostate cancer, and chronic fatigue syndrome

Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so I’ll provide a summary of …

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XMRV in human respiratory tract

An important question about the retrovirus XMRV, which has been implicated in prostate cancer and chronic fatigue syndrome, is where the virus replicates in humans. Such information would provide clues about how infection might be transmitted. To date the virus has been detected in malignant prostate cells and in the peripheral blood mononuclear cells and …

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Google Flu Trends is not accurate

Google Flu Trends uses analysis of large numbers of search queries to track influenza-like illness in a population. The idea is that the frequency of certain queries correlates with the percentage of physician visits in which a patient presents with influenza-like symptoms. Google claims that it can accurately estimate the level of weekly influenza activity …

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