As a virologist who has worked on poliovirus since 1979, I would be remiss if I did not note that today, 24 October, is World Polio Day. World Polio Day was established by Rotary International over a decade ago to commemorate the birth of Jonas Salk, who led the first team to develop a vaccine against …
I interviewed Harald zur Hausen, MD., recipient of the 2008 Nobel Prize in Physiology or Medicine, in Manchester UK at the 2013 meeting of the Society for General Microbiology. We spoke about his career, his work leading to the discovery that human papillomavirus types 16 and 18 are causative agents of cervical cancer, and his …
Hepatitis B virus (HBV, illustrated) is a substantial human pathogen. WHO estimates that there are now 240,000,000 individuals chronically infected with HBV worldwide, of which 25% will die from chronic liver disease or hepatocellular carcinoma. The hepatitis B virus vaccine is highly effective at preventing infection. Because there are no known animal reservoirs of the …
We have been using HeLa cells in my laboratory since 1982, when I arrived at Columbia University Medical Center fresh from postdoctoral work with David Baltimore at MIT. I brought with me a line of HeLa cells and used them for 30 years for our research on viruses. Here is a story of how we …
When virologists Fouchier and Kawaoka were isolating avian influenza H5N1 viruses that could transmit among ferrets by aerosol, there was consternation from some quarters that such viruses might escape from the laboratory and cause a pandemic in humans. Part of the fear came from the fact that the case fatality ratio for human infections with …
Incidence of asymptomatic human influenza A(H5N1) virus infection Read More »
En esta sesión discutiremos como los virus con genoma de DNA replican sus ácidos nucleÃcos. Consideraremos las enzimas y otras proeteÃnas que participan en la sÃntesis del DNA viral y los retos que imponen las distintas topologÃas de los genomas de DNA (DNA linear de cadena sencilla, DNA circular de doble cadena y DNA linear …
Virologia en Español Clase #7 €“ Replicación de Virus con Genoma de DNA Read More »
