Basic virology

A lesson from SARS-CoV for 2019-nCoV

As with all previous outbreaks of new virus infections, we are being warned of impending doom concerning the new coronavirus, 2019-nCoV that is now spreading globally. China€™s National Health Commission Vice Minister Li Bin recently warned that ‘there is the possibility of viral mutation€™. Perhaps Mr. Li is unaware that viral genomes sustain mutations during …

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An ancestral vector improves on this year€™s model

Adenovirus associated virus (AAV) vectors are being increasingly used for gene therapy because they are not pathogenic in humans and persist for long periods in certain cell types. Currently 120 gene delivery clinical trials with these vectors are in progress, and two have been approved: Luxturna to treat a rare form of blindness, and another …

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