By David Tuller, DrPH Earlier today, I sent the following letter to Dr David Perez, a neurologist and psychiatrist at Massachusetts General Hospital in Boston. Dr Perez, an expert on functional neurological disorders, wrote a commentary for Lancet Psychiatry that accompanied the publication of the results for CODES, a major study of cognitive behavior therapy …
Trial By Error: My Letter to Author of CODES Commentary Read More »
By David Tuller, DrPH By all accounts, the recently published CODES trial was the most authoritative study to date of whether cognitive behavior therapy (CBT) was an effective treatment for so-called dissociative seizures–a point confirmed in a commentary accompanying the paper in Lancet Psychiatry. Unfortunately, the CODES investigators and the commentary author seem to interpret …
Trial By Error: CODES Trial Commentary Promotes ‘Eminence-Based Medicine’ Read More »
By David Tuller, DrPH UK Funding for Major Genetics ME Study Two of the UK’s largest public funding agencies announced this week that they would provide £3.2 million (around $4 million at current rates) for a study that will analyze genetic material from as many as 20,000 people to search for underlying causes of myalgic …
Trial By Error: UK Funds Genetics Project; My Letter to CODES Investigators Read More »
By David Tuller, DrPH [*In the last paragraph, I mistakenly referred to the CODES protocol rather than the CODES statistical analysis plan. I apologize for the error.] I have recently written about CODES, the high-profile clinical trial investigating whether cognitive behavior therapy (CBT) could reduce the frequency of dissociative seizures, also known as psychogenic non-epileptic …
Trial By Error: More Questions About CODES Trial of CBT for Seizures Read More »
By David Tuller, DrPH Earlier this week, I sent a nudge to Professor Imti Choonara, editor-in-chief of BMJ Paediatrics Open, and Fiona Godlee, editorial director of BMJ, about a problematic “feasibility study” published a few months ago. That followed a letter two weeks ago, to which I had not received a response. Previous posts on …
Trial By Error: BMJ Responds to Appeals About Norway’s CBT-Music Therapy Study Read More »
Lancet Psychiatry recently published the results of a high-profile trial of cognitive behavior therapy as a treatment for so-called dissociative seizures, also known as psychogenic non-epileptic seizures. The trial, nicknamed CODES, found that CBT had no impact on seizure frequency–the primary outcome. The average number of seizures per month dropped in both the treatment and …
Trial By Error: Trio of Trials Shows Limits of CBT for Medically Unexplained Symptoms Read More »
