Author name: David Tuller

Trial By Error: A Letter Seeking a Correction in FMD Physiotherapy Paper

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By David Tuller, DrPH I have recently written about a trial of an intervention for functional motor disorder (FMD) that had null results for its primary outcome—physical function as rated by the SF-36. The study–“Specialist Physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial,” published by …

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Trial By Error: When Primary Outcomes Yield Null Results in Clinical Trials, FND Experts Prefer Their Secondary Outcomes

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By David Tuller, DrPH In 2020, the CODES study of cognitive behavior therapy (CBT) for psychogenic non-epileptic seizures, also known as dissociative seizures, reported null findings for its primary outcome—the number of seizures per month one year after the start of therapy. This was a disappointing result for an ambitious effort to seek an effective …

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Trial By Error: Australian GPs Keep Promoting Exercise Treatments for ME/CFS

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By David Tuller, DrPH When it comes to treatments for ME/CFS, the Royal Australian College of General Practitioners (RACGP) has long endorsed the graded exercise therapy (GET)/cognitive behavioral therapy (CBT) approach. Last April, the organization published an “updated” article in its Handbook of Non-Drug Interventions (HANDI) advocating “incremental physical activity” for what it called CFS/ME. …

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Trial By Error: Andrew Ewing & David Joffe on Just-Published “Global Expert Consensus” on Long Covid

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By David Tuller, DrPH *This is a crowdfunding period at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 Last week, the journal Annals of Clinical Microbiology and Antimicrobials published the results of …

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Trial By Error: #MEAction’s Jaime Seltzer on Where We’ve Been, What We’ve Learned, and Where Things Are Now

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By David Tuller, DrPH *This is a crowdfunding period at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 It’s been five years, more or less, since the start of the coronavirus pandemic–and …

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Trial By Error: In a Compelling Documentary, Five Doctors Discuss Being Sick

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By David Tuller, DrPH *This is a crowdfunding period at University of California, Berkeley. If you appreciate my work and would like to make a donation (tax-deductible to US taxpayers) to the university in support of my position, here’s the link: https://crowdfund.berkeley.edu/project/46120 ********** I first connected with Anil van der Zee, a severe ME patient in …

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