The gut tracts of many animals are inhabited by a microbial community composed of bacteria, archaea, fungi, and viruses. The interplay among these inhabitants can have an impact on health and disease. Mosquitoes are no exception – replication of dengue virus in the gut tract is modulated by a fungus and a bacterium.
The family of viruses known as the Filoviridae (filo, from the Latin for thread) is well known for the ebolaviruses, which cause the hemorrhagic disease that regularly erupts in Africa. As Earth€™s virome is slowly revealed, other filoviruses are discovered.
The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus. Click arrow to play Download TWiV 532 (60 MB .mp3, 99 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Measles virus does not just cause a rash – it can kill, up to 100,000 people each year. And there are many related viruses circulating in other animals that are not far from being able to infect human cells.
Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses. Click arrow to play Download TWiV 530 (65 MB .mp3, 107 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
The diversity of cellular RNA structure and function has progressed from the early days of molecular biology, when we thought only about mRNA, tRNA and ribosomal RNAs. Then RNA splicing was discovered along with the many small nuclear RNAs that mediate that process. Next came small interfering RNAs and microRNAs and long noncoding RNAs, master …
