Virology

A Viral Risk Factor for Lupus

by Gertrud U. Rey Characteristic butterfly rash associated with lupus flares. Photo credit: Vecteezy. Epstein-Barr virus (EBV) is a common human herpesvirus that typically spreads through saliva and is known for causing infectious mononucleosis (i.e., “mono”). There is an established causal link between infection with EBV and the development of ...

Vaccine Modalities – Part 2

by Gertrud U. Rey Last month’s post provided an overview of various traditional vaccine technologies. The current post highlights more recent advances in the field. Genetic vaccines introduce nucleic acids (DNA and/or RNA) into a recipient’s cells. Once inside the cells, these genetic instructions are used by the cell’s machinery ...

Vaccine Modalities – Part 1

by Gertrud U. Rey During the last 50 years, vaccination efforts have prevented about 154 million deaths worldwide, with the measles vaccine alone responsible for a large portion of this achievement. Childhood vaccinations in particular have not only led to a 40% reduction in global infant deaths throughout the same ...

A Universal Antiviral Drug

by Gertrud U. Rey There is currently no vaccine that is effective against all viruses and it is unlikely that one will ever exist. But what about a universal antiviral drug? A recent study out of Columbia University suggests that it might be possible to develop effective broad-spectrum antivirals against ...

The Deadliest Virus

by Gertrud U. Rey Rabies virus has a characteristic bullet-shaped virion structure. Rabies virus infection in mammals is nearly 100% fatal if left untreated. The signs and symptoms that precede death – agitation, anxiety, hallucinations, hydrophobia, excessive salivation, and biting - have inspired countless fictional characters and narratives. The recent ...
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