2015

Wasps do a gain-of-function experiment in caterpillars

3 Comments / Basic virology, Information / By

Parasitic wasps (in the order Hymenoptera) inject their eggs into lepidopteran hosts, where the eggs go through their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins that inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepidopteran host where they have assumed new defensive functions against other …

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TWiV 355: Baby’s first virome

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On episode #355 of the science show This Week in Virology, the TWiV team considers the effect of a Leishmaniavirus on the efficacy of drug treatment, and the human fecal virome and microbiome in twins during early infancy. You can find TWiV #355 at www.microbe.tv/twiv.

A virus in a parasite in a human

3 Comments / Basic virology, Information / By

The protozoan parasite Leishmania, transmitted to humans by the bite of a sandfly, may cause disfiguring skin lesions. A virus within the parasite appears to increase the risk of treatment failure with anti-leishmania drugs. A double-stranded RNA virus was found over 20 years ago to infect different species of Leishmania, with up to 50% of clinical isolates …

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TWiV 354: The cat in the HAART

This Week in Virology / By

On episode #354 of the science show This Week in Virology, the esteemed doctors of TWiV review a new giant virus recovered from the Siberian permafrost, why influenza virus gain of function experiments are valuable, and feline immunodeficiency virus. You can find TWiV #354 at www.microbe.tv/twiv.

Why do we still use Sabin poliovirus vaccine?

26 Comments / Basic virology, Information / By

The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a brief visit to the history of poliovirus vaccines. The inactivated poliovirus vaccine (IPV) developed by …

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ASM Live at ICAAC/ICC 2015

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ASM Live will be broadcast from ICAAC/ICC 2015 in San Diego, CA, where host Michael Schmidt, PhD, Professor and Vice Chairman of Microbiology and Immunology at the Medical University of South Carolina, and co-host of This Week in Microbiology, will interview researchers about their work. Streaming will take place at the San Diego Convention Center, Room 29B, and meeting registrants …

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