Virology lecture #22: Evolution 4 Comments / By Vincent Racaniello / 10 May 2010 Download: .wmv (393 MB) | .mp4 (102 MB) Visit the virology W3310 home page for a complete list of course resources.
4 thoughts on “Virology lecture #22: Evolution”
Why doesn't HIV form plaques in any types of cells?
I'm not sure that anyone has tried very hard to develop a plaque
assay. The virus is cytopathic, yet the relevant cells for infection
are lymphocytes, which don't adhere to plastic dishes. Therefore
developing a plaque assay would not be straightforward.
The researchers extracted white blood cells from all the subjects and exposed them to HIV in a culture dish. They reported in the journal BMC Immunology that HIV replication was slowed by about 80% in the cells from those who had received smallpox vaccination.
nice theme. but it takes a while to load
Comments are closed.