Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, and Rich Condit On episode #41 of the podcast “This Week in Virology”, Vincent, Dick, Alan and Rich Condit chat about infectious salmon anemia virus, virus-resistant grapevines, virulence of pandemic H1N1 influenza virus, origin of 1918 influenza virus, holy water ban to halt influenza, frequency of human WU and …
Dispensers of alcohol-based rubs are appearing in public places in an attempt to reduce the spread of pandemic influenza. Are these effective at removing virus from hands? In a recent study, the hands of twenty vaccinated, antibody-positive volunteers were contaminated with 10,000,000 TCID50 of a 1999 seasonal H1N1 influenza virus strain (see this post for …
The results of experiments comparing the virulence in animals of the 2009 H1N1 influenza virus with seasonal strains have spawned the headline Study Suggests H1N1 Virus More Dangerous Than Suspected. In my view, the best experiment is now being done in humans: infection of millions with the pandemic virus. The results show that the virus …
Is the 2009 H1N1 influenza virus more dangerous than we think? Read More »
The plaque assay is a terrific method for determining virus titers, but it doesn’t work for all viruses. Fortunately there are several alternative methods available, including the end-point dilution assay. The end-point dilution assay was used to measure virus titer before the development of the plaque assay, and is still used for viruses that do …
Measurement of viruses by end-point dilution assay Read More »
Hosts: Vincent Racaniello, Dick Despommier, and Alan Dove On episode #40 of the podcast “This Week in Virology”, Vincent, Dick, and Alan consider Reston ebolavirus in swine, historical perspective of H1N1 influenza virus emergence and circulation, Tamiflu-resistant H1N1, Tamiflu in Japanese river waters, transmission of H1N1 virus in ferrets, and pneumonia and respiratory failure from H1N1 …
Tamiflu (Oseltamivir) is one of the few antiviral drugs available for treatment of influenza. Use of the drug has increased substantially because of the emergence of the 2009 H1N1 pandemic strain, against which no vaccine is yet available. A recent study has shown that low levels of oseltamivir can be detected in the aquatic environment. …
