Virology
TWiV 523: Virology in Zürich
By Vincent Racaniello
https://youtu.be/SiS0plM4i9k At the University of Zürich, Vincent speaks with virologists Cornel Fraeful, Urs Greber, and Silke Stertz about their careers and their work on AAV2, adenovirus entry, and influenza virus. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" ...
TWiV 522: Readers of the lost ORF
By Vincent Racaniello
The TWiVsters review isolation of a naturally occurring DNA virus from fruit flies, and the cell-type specific function of a small transmembrane protein encoded in an open reading frame upstream of the enterovirus polyprotein. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; ...
The lost picornavirus ORF
By Vincent Racaniello
For over 50 years the RNA genome of picornaviruses (illustrated below for poliovirus) was thought to be translated into a single, long polyprotein. All this time a very small upstream open reading frame (uORF) has gone undetected - until now. Analysis of over 3000 picornavirus genomes revealed a small ORF, ...
TWiV 521: Spitting in the Allee
By Vincent Racaniello
Team TWiV cover the discovery of another giant virus from 30,000 year old Siberian permafrost, and how viral aggregation accelerates the production of new infectious viruses and increases fitness, demonstrating an Allee effect. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span><span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: ...
Paul Has Measles
By Vincent Racaniello
Susana López, Martha Yocupicio, Selene Zárate, virologists from Mexico, together with graphic illustrator Eva Lobatón, have teamed up to produce Paul Has Measles, a children's book about viruses and vaccines. Paul Has Measles is available as a free pdf in 16 languages. It may also be purchased as a Kindle or ...