Top view of calicivirus portal. VP1 is green, VP2 is red. Virus particles are metastable: they must be highly stable, to protect the nucleic acid while traveling from host to host or cell to cell, and then come apart to liberate the genome into the cell. New insight into this ...

The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA. Click arrow to play Download TWiV 534 (57 MB .mp3, 95 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

The gut tracts of many animals are inhabited by a microbial community composed of bacteria, archaea, fungi, and viruses. The interplay among these inhabitants can have an impact on health and disease. Mosquitoes are no exception - replication of dengue virus in the gut tract is modulated by a fungus ...

The family of viruses known as the Filoviridae (filo, from the Latin for thread) is well known for the ebolaviruses, which cause the hemorrhagic disease that regularly erupts in Africa. As Earth€™s virome is slowly revealed, other filoviruses are discovered. The first filovirus discovered was Marburg virus, first described in ...

The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus. Click arrow to play Download TWiV 532 (60 MB .mp3, 99 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv