Virology
The evolving concept of virus
By Vincent Racaniello
In the 19th century the word 'virus€™ was used to describe the cause of any contagious disease. How it came to describe the very small intracellular parasites that we know today is a fascinating story that illustrates our evolving concepts of infectious agents. Long before bacteria, fungi, and viruses were ...
TWiV 561: Hot or not
By Vincent Racaniello
The Autonomous CollecTWiVe reveal two effective treatments for Ebolavirus infection, how a virus in a fungus confers heat tolerance to a plant, and dampened inflammation as a mechanism for bat tolerance to viral infection. Click arrow to play Download TWiV 561 (57 MB .mp3, 93 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show ...
Enterovirus D68 and childhood paralysis
By Vincent Racaniello
The Centers for Disease Control and Prevention thinks that viruses play a role in the childhood paralysis called acute flaccid myelitis (AFM). The finding of antibodies to enterovirus D68 (EV-D68) in the cerebrospinal fluid of patients with AFM strengthens the link between infection with this virus and AFM. Acute flaccid ...
TWiV 560: CEIRS, influenza and company
By Vincent Racaniello
https://youtu.be/4O2j3n1RBiA From the meeting of the Centers of Excellence for Influenza Research and Surveillance, Vincent speaks with Alan, Florian and Jennifer about their careers, the purpose of CEIRS, universal influenza vaccines, and cellular responses to infection in pediatric populations. Click arrow to play Download TWiV 560 (37 MB .mp3, 61 min) Subscribe ...
Avoiding error catastrophe with recombination
By Vincent Racaniello
RNA viruses exist close to their error threshold, the point beyond which additional mutations cause loss of infectivity. It has been suggested that RNA recombination prevents viruses from exceeding the error threshold - a situation called error catastrophe - but there has been little experimental support for this hypothesis. An ...
