Daniel Griffin provides a clinical update on COVID-19, then we review SARS-CoV-2 infections in non-humans, vesicular stomatitis in Kansas horses, and answer listener questions. Click arrow to playDownload TWiV 632 (87 MB .mp3, 144 min)Subscribe (free): iTunes, Google Podcasts, RSS, emailBecome a patron of TWiV!Show notes at microbe.tv/twiv

Most of the 172 SARS-CoV-2 vaccines in development will be administered by intramuscular injection, a traditional route for many effective vaccines. In my opinion the use of needles for immunization will one day be replaced by microneedle patches, which can not only be self-administered but have a variety of other ...

Vincent, Rich, and Brianne discuss a study estimating the fraction of symptoms and severe disease after SARS- CoV-2 infection, cellular immune responses without seroconversion during interfamilial infections, and answer listener email. Click arrow to playDownload TWiV 631 (72 MB .mp3, 119 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

Jessie, Allie and Tyler join Nels and Vincent to describe their work on deep mutational scanning of the SARS-CoV-2 receptor binding domain. Click arrow to playDownload TWiEVO 57  (50 MB .mp3, 84 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Show notes at microbe.tv/twievo

Daniel Griffin provides a clinical update on COVID-19, including analysis of the dexamethasone trial, and then we discuss two Ebolavirus outbreaks in DRC, clinical and virological aspects of asymptomatic SARS-CoV-2 infections, age-dependent effects on transmission, and answer listener email. https://youtu.be/OvJWgzQI7b0 Click arrow to playDownload TWiV 629 (95 MB .mp3, 158 min)Subscribe ...